Purinostat
Purinostat mesylate is a selective HDACI/IIb inhibitor that suppresses Ph+ and CML-derived CD34+ leukemic cell survival by targeting key LSC factors like c-Myc and β-Catenin. It has demonstrated anti-leukemic activity in both in vitro and in vivo research models, impacting pathways such as glutamate metabolism via GLS1.
Product Specifications
CAS Number
1929583-17-4
Field of Research
Epigenetics & Chromatin, Molecular Biology
Smiles
O=C (NO) C1=CN=C (N=C1) N (C) CC2=NC=3C (=NC (=NC3N4CCOCC4) C=5C=CC (N) =CC5) N2C
Molecular Formula
C23H26N10O3
Molecular Weight
490.518
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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