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RORγt inverse agonist 34

Compound 5a (34) is a potent RORγt inverse agonist with an IC50 of 94 nM against the ligand-binding domain. It is a valuable research tool for investigating Th17-driven pathologies, such as psoriasis, in both cellular and animal model studies.

Product Specifications

CAS Number

2247604-77-7

Field of Research

Metabolism Research, Pharmacology & Drug Discovery

Smiles

O=C1C2=CC=C (C=C2CCC1) NC3=CC=C4C (=C3) CCCN4S (=O) (=O) N (C) CC5=CC=C (C=C5) C (C) (C) C

Molecular Formula

C31H37N3O3S

Molecular Weight

531.709

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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