RORγt inverse agonist 34
Compound 5a (34) is a potent RORγt inverse agonist with an IC50 of 94 nM against the ligand-binding domain. It is a valuable research tool for investigating Th17-driven pathologies, such as psoriasis, in both cellular and animal model studies.
Product Specifications
CAS Number
2247604-77-7
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Smiles
O=C1C2=CC=C (C=C2CCC1) NC3=CC=C4C (=C3) CCCN4S (=O) (=O) N (C) CC5=CC=C (C=C5) C (C) (C) C
Molecular Formula
C31H37N3O3S
Molecular Weight
531.709
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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