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DQ661

DQ661 is a dimeric quinacrine-based compound that potently inhibits PPT1 and autophagy. It suppresses mTORC1 activity, reducing pS6K T389 and pS6 S240/244 protein levels, and demonstrates anticancer properties in research models. This small molecule is used in studies investigating autophagy, mTOR signaling, and oncology in both cellular and in vivo experiments.

Product Specifications

CAS Number

2027551-01-3

Field of Research

Cell Biology, Signal Transduction

Smiles

ClC=1C=CC=2C (=NC=3C=CC (OC) =CC3C2NCCCCCCN (C) CCCCCCNC4=C5C=CC (Cl) =CC5=NC=6C=CC (OC) =CC64) C1

Molecular Formula

C41H47Cl2N5O2

Molecular Weight

712.75

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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