DQ661
DQ661 is a dimeric quinacrine-based compound that potently inhibits PPT1 and autophagy. It suppresses mTORC1 activity, reducing pS6K T389 and pS6 S240/244 protein levels, and demonstrates anticancer properties in research models. This small molecule is used in studies investigating autophagy, mTOR signaling, and oncology in both cellular and in vivo experiments.
Product Specifications
CAS Number
2027551-01-3
Field of Research
Cell Biology, Signal Transduction
Smiles
ClC=1C=CC=2C (=NC=3C=CC (OC) =CC3C2NCCCCCCN (C) CCCCCCNC4=C5C=CC (Cl) =CC5=NC=6C=CC (OC) =CC64) C1
Molecular Formula
C41H47Cl2N5O2
Molecular Weight
712.75
Storage Conditions
-20°C
Notes
For research use only.
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