GK420
GK420 (AVX420) is a potent and selective cPLA2α inhibitor with an XI (50) of 0.0016, effectively blocking arachidonic acid release (EC50 = 0.09 μM) . This tool compound is widely used in cancer research to investigate lipid signaling pathways in both cellular and animal models of inflammation and oncology.
Product Specifications
CAS Number
1621517-60-9
Field of Research
Metabolism Research
Smiles
O=C (OC) C=1N=C (SC1) C (=O) COC2=CC=C (OCCCCCCC) C=C2
Molecular Formula
C20H25NO5S
Molecular Weight
391.481
Storage Conditions
-20°C
Notes
For research use only.
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