PKM2-IN-8
PKM2-IN-8 (Compound 9b) is a potent pyruvate kinase M2 (PKM2) inhibitor (IC50 = 0.31 μM) with antiproliferative effects in U87MG glioma cells. It induces apoptosis, reduces lactate production, and serves as a valuable research tool for studying glioblastoma metabolism in vitro.
Product Specifications
CAS Number
3115004-02-6
Field of Research
Cell Biology, Metabolism Research
Smiles
C1=CC=C2C=C (C=CC2=C1) C3=NN (N=N3) CC (=O) C4=CN=C5N4C=CC=N5
Molecular Formula
C19H13N7O
Molecular Weight
355.353
Storage Conditions
-20°C
Notes
For research use only.
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