HSN748
HSN748 is a ponatinib analog and multi-kinase inhibitor targeting FLT3, ABL1, RET, PDGFRα/β, MNK1, and MNK2. It demonstrates efficacy in suppressing the proliferation of both chronic and acute myeloid leukemia cell lines in vitro, supporting its use as a research tool in leukemia studies.
Product Specifications
CAS Number
2409925-53-5
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
O=C (NC1=CC=C (C (=C1) C (F) (F) F) CN2CCN (C) CC2) C=3C=NC=C (C#CC4=CN=C5C=CC=NN45) C3
Molecular Formula
C27H24F3N7O
Molecular Weight
519.521
Storage Conditions
-20°C
Notes
For research use only.
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