VEGFR-2-IN-58
VEGFR-2-IN-58 (Compound 7b) is a potent and selective VEGFR-2 inhibitor (IC50 = 42.5 nM) with anticancer activity. It induces G2/M cell cycle arrest, promotes apoptosis via BAX/Bcl-2 modulation, and inhibits cell migration in vitro, supporting its use in angiogenesis and oncology research.
Product Specifications
CAS Number
3066972-97-9
Field of Research
Cardiovascular Research, Cardiovascular Research; Cell Biology, Cell Biology, Signal Transduction
Smiles
C1=CC=C (C=C1) C2=C (OC (=C2C#N) /N=C/NC3=CC=C (C=C3) Cl) C4=CC=CC=C4
Molecular Formula
C24H16ClN3O
Molecular Weight
397.856
Storage Conditions
-20°C
Notes
For research use only.
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