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P2X4 antagonist-4

P2X4 antagonist-4 (compound 64) is a selective P2X4 receptor blocker (IC50 = 8 μM) that suppresses ATP-mediated NLRP3 inflammasome activation and IL-1β release. This tool compound is useful for studying neuropathic pain and neuroinflammation in both cellular and animal models of disease.

Product Specifications

CAS Number

3108486-39-8

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Smiles

CC1=C (C=CC (=C1) F) CS (=O) (=O) NC2=CC=C (C=C2) N3C (=O) CC (=O) NC4=C3C=CC5=CC=CC=C54

Molecular Formula

C27H22FN3O4S

Molecular Weight

503.545

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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