P2X4 antagonist-4
P2X4 antagonist-4 (compound 64) is a selective P2X4 receptor blocker (IC50 = 8 μM) that suppresses ATP-mediated NLRP3 inflammasome activation and IL-1β release. This tool compound is useful for studying neuropathic pain and neuroinflammation in both cellular and animal models of disease.
Product Specifications
CAS Number
3108486-39-8
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Smiles
CC1=C (C=CC (=C1) F) CS (=O) (=O) NC2=CC=C (C=C2) N3C (=O) CC (=O) NC4=C3C=CC5=CC=CC=C54
Molecular Formula
C27H22FN3O4S
Molecular Weight
503.545
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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