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SARS-CoV-2 PLpro-IN-1

SARS-CoV-2 PLpro-IN-1 is a potent, non-covalent competitive inhibitor of the SARS-CoV-2 papain-like protease (PLpro), demonstrating an IC50 of 15.06 μM and a Ki of 22.93 μM. It also exhibits antiviral activity in vitro, inhibiting Vero cell proliferation with an IC50 of 7.47 μM, making it a valuable tool for studying coronavirus replication and host-pathogen interactions.

Product Specifications

CAS Number

3053753-61-7

Field of Research

Infectious Disease & Virology

Smiles

N (C=1C2=C (C=CC (=N2) C=3C=CC (OC) =NC3) N=CC1) [C@@H]4CCNC4

Molecular Formula

C18H19N5O

Molecular Weight

321.376

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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