SEH inhibitor-19
SEH inhibitor-19 ((R) -14i) is a potent, orally bioavailable soluble epoxide hydrolase inhibitor (IC50 = 1.2 nM) . It demonstrates anti-inflammatory activity by reducing TNF-α and IL-6 expression, validated in models of acute pancreatitis and Carrageenan-induced paw edema.
Product Specifications
CAS Number
3107483-12-2
Field of Research
Cell Biology, Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery
Smiles
COC1=C (C=C2[C@H]3CC4=C (CN3CCC2=C1) C=C (C=C4) NC (=O) NCC5=CC=C (C=C5) OC (F) (F) F) OC
Molecular Formula
C28H28F3N3O4
Molecular Weight
527.535
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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