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FW-1

FW-1 is a potent and selective type I FLT3 inhibitor (IC50 ~1 μM) for research use. It demonstrates anti-proliferative activity by inducing G0/G1 cell cycle arrest and apoptosis in FLT3-mutant AML cell lines like MV4-11 and MOLM-13, supporting its investigation in hematological malignancy research.

Product Specifications

CAS Number

3094389-92-8

Field of Research

Cardiovascular Research, Cell Biology, Signal Transduction

Smiles

CN1CCN (CC1) CC2=CC=C (C=C2) NC3=NC4=C (C (=C3) NC5=CC=CC=C5) C (=NO4) N

Molecular Formula

C24H27N7O

Molecular Weight

429.517

Storage Conditions

-20°C

Notes

For research use only.

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