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MLK3-IN-1

MLK3-IN-1 (Compound 37) is a potent and selective mixed-lineage kinase 3 (MLK3) inhibitor (IC50 <1 nM) with excellent metabolic stability in liver microsomes. It also inhibits FAK at a much higher IC50 of 15.5 μM. This tool compound is used in biochemical and cellular research to investigate MLK3 signaling pathways in cancer and inflammatory diseases.

Product Specifications

Field of Research

Cardiovascular Research, Signal Transduction

Smiles

CS (=O) (=O) C1=CC=CC (=C1) CNC2=NC (=NC=C2C (F) (F) F) NC3=CC=C (C=C3) C (F) (F) F

Molecular Formula

C20H16F6N4O2S

Molecular Weight

490.422

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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