MLK3-IN-1
MLK3-IN-1 (Compound 37) is a potent and selective mixed-lineage kinase 3 (MLK3) inhibitor (IC50 <1 nM) with excellent metabolic stability in liver microsomes. It also inhibits FAK at a much higher IC50 of 15.5 μM. This tool compound is used in biochemical and cellular research to investigate MLK3 signaling pathways in cancer and inflammatory diseases.
Product Specifications
Field of Research
Cardiovascular Research, Signal Transduction
Smiles
CS (=O) (=O) C1=CC=CC (=C1) CNC2=NC (=NC=C2C (F) (F) F) NC3=CC=C (C=C3) C (F) (F) F
Molecular Formula
C20H16F6N4O2S
Molecular Weight
490.422
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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