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GSK-3β inhibitor 24

GSK-3β inhibitor24 (Compound 41) is a highly potent, sub-nanomolar inhibitor (IC50 = 0.22 nM) that modulates key Alzheimer's disease pathways. It reduces pathological tau phosphorylation while promoting β-catenin signaling and neurogenesis markers, demonstrating therapeutic potential in both cellular and animal models of neurodegeneration.

Product Specifications

Field of Research

Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology

Smiles

C1OC2=C (O1) C=C (C=C2) C3=C (C=NC=C3) NC (=O) C4=CNC5=C4C=C (C=N5) C6=CC=CC=C6

Molecular Formula

C26H18N4O3

Molecular Weight

434.446

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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