IL-17-IN-3
IL-17-IN-3 (compound 11) is a potent small molecule inhibitor of IL-17A, demonstrating an IC50 of 35 nM. It has shown good tolerability in a rat model at doses up to 300 mg/kg/day for four days, supporting its utility for investigating IL-17-mediated pathways in both cellular and animal studies of autoimmune diseases.
Product Specifications
Field of Research
Immunology & Inflammation
Smiles
C1CC1/C=C (\C (=O) N[C@@H] (C2CCC (CC2) (F) F) C (=O) NC3=NC=C (S3) CN4C[C@H] (NC4=O) C (F) (F) F) /F
Molecular Formula
C22H25F6N5O3S
Molecular Weight
553.521
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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