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ChREBPα/14-3-3 regulator-1

Compound 43 is a selective molecular glue that stabilizes the ChREBP/14-3-3 interaction (EC50 = 3.8 μM) . It protects pancreatic β-cells from glucolipotoxicity in vitro, preserving their function and highlighting its utility for type 2 diabetes and metabolic disease research.

Product Specifications

Field of Research

Pharmacology & Drug Discovery

Smiles

C1=CC=C (C (=C1) OCC (=O) NCC (C2=CC (=CC=C2) F) (F) F) P (=O) (O) O

Molecular Formula

C16H15F3NO5P

Molecular Weight

389.263

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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