ChREBPα/14-3-3 regulator-1
Compound 43 is a selective molecular glue that stabilizes the ChREBP/14-3-3 interaction (EC50 = 3.8 μM) . It protects pancreatic β-cells from glucolipotoxicity in vitro, preserving their function and highlighting its utility for type 2 diabetes and metabolic disease research.
Product Specifications
Field of Research
Pharmacology & Drug Discovery
Smiles
C1=CC=C (C (=C1) OCC (=O) NCC (C2=CC (=CC=C2) F) (F) F) P (=O) (O) O
Molecular Formula
C16H15F3NO5P
Molecular Weight
389.263
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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