KRAS inhibitor-40
KRAS inhibitor-40 is a small molecule that disrupts the KRAS G12C-BRAF complex, inhibiting downstream ERK signaling and tumor cell proliferation. It is used in cancer research, particularly for studying KRAS-driven tumors, and has demonstrated activity in both in vitro cellular assays and in vivo xenograft models.
Product Specifications
CAS Number
3059496-56-6
Field of Research
Cell Biology, Pharmacology & Drug Discovery, Signal Transduction
Smiles
O=C1OCC (C) (C) CC=2C=3C=C (C=C4C3N (C2C5=CC (=CN=C5C (OC) C) N6CCOCC6) CC (F) (F) C4) C=7N=C (SC7) CC (NC (=O) C (N (C (=O) C8 (F) CCN (C (=O) C (F) Cl) CC8) C) C (C) C) C (=O) N9NC1CCC9
Molecular Formula
C53H66ClF4N9O8S
Molecular Weight
1100.66
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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