SIRT6-IN-4
SIRT6-IN-4 (Compound 10d) is a selective SIRT6 inhibitor (IC50 = 5.68 μM) with anti-cancer properties. It inhibits proliferation, migration, and invasion of MCF-7 cells in vitro, induces G2/M arrest and apoptosis, and demonstrates in vivo antitumor activity in mouse models.
Product Specifications
Field of Research
Cell Biology, Epigenetics & Chromatin, Molecular Biology
Smiles
C1=CC=NC (=C1) CNC (=O) C2=NC=C3C (=C2) C4=C (N3CC5=CC=C (C=C5) C#N) C=CC (=C4) Cl
Molecular Formula
C26H18ClN5O
Molecular Weight
451.907
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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