CDK4/6-IN-23
CDK4/6-IN-23 (Compound 42) is a potent, selective CDK4/6 inhibitor with an IC50 of 11 nM against CDK6. It exhibits immunomodulatory activity by activating immune cells and increasing IL-3 production. In vivo studies in 5-FU-treated mice show it provides bone marrow protection alongside its immunoenhancing effects.
Product Specifications
Field of Research
Cell Biology, Signal Transduction
Smiles
CC (=O) N1CCC2 (CC1) CC (=O) C3=C (O2) C=C (C=C3) C4=NC (=NC=C4F) NC5=NC=C (C=C5) N6CCN (CC6) C (=O) C7CC7
Molecular Formula
C32H34FN7O4
Molecular Weight
599.655
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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