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MAT2A-IN-21

MAT2A-IN-21 (compound 28) is a potent and selective small molecule inhibitor of methionine adenosyltransferase 2A (MAT2A), exhibiting an IC50 of 49 nM. It is a valuable research tool for studying MTAP-deleted cancers in both cellular and animal models, enabling investigation into metabolic vulnerabilities and potential therapeutic strategies.

Product Specifications

CAS Number

3062073-94-0

Field of Research

Epigenetics & Chromatin, Signal Transduction

Smiles

O=C1C (=NC=2C=CC (=CC2N1C3=CC=C (OC (F) F) C=C3) C4CC4) C=5C=CC=6N=CN (C6C5) C

Molecular Formula

C26H20F2N4O2

Molecular Weight

458.459

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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