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MTHFD2-IN-5

MTHFD2-IN-5 (Compound 16e) is a potent and selective MTHFD2 inhibitor with an IC50 of 66 nM. It exhibits anti-proliferative activity in MOLM-14 cells (GI50 = 720 nM) and has shown in vivo antitumor efficacy in mouse models, supporting its use in oncology and metabolic enzyme research.

Product Specifications

Field of Research

Metabolism Research

Smiles

C1=CC (=C (C=C1C (=O) N[C@@H] (CCC (=O) O) C (=O) O) Cl) NC (=O) NC2=C (N=C (NC2=O) N) N

Molecular Formula

C17H18ClN7O7

Molecular Weight

467.821

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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