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RORγt inverse agonist 33

RORγt inverse agonist 33 (compound (R) -D4) is an orally active small molecule with an IC50 of 21 nM. It is a valuable research tool for investigating Th17 cell biology and has demonstrated efficacy in preclinical models of autoimmune diseases, including rheumatoid arthritis.

Product Specifications

Field of Research

Metabolism Research, Pharmacology & Drug Discovery

Smiles

CC[C@@H]1CCC2=C (N1S (=O) (=O) C3=CC (=C (C=C3) COC4CCOCC4) CO) C=CC (=C2) C (C) C

Molecular Formula

C27H37NO5S

Molecular Weight

487.651

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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