MOR modulator-1

MOR modulator-1 (compound 6) is a potent and selective μ opioid receptor (MOR) antagonist with Ki values of 0.25, 41.1, and 1.30 nM for μ, δ, and κ receptors, respectively. It demonstrates superior selectivity and reduced withdrawal effects compared to NAT, making it a valuable tool for in vivo behavioral studies and in vitro receptor binding assays in opioid research.