PAR-2-IN-2
PAR-2-IN-2 (P-596) is a selective small molecule antagonist of protease-activated receptor 2 (PAR-2), inhibiting the SLIGKV peptide with an IC50 of 10.79 μM while showing significantly weaker activity against trypsin (IC50 >200 μM) . This compound is a valuable research tool for studying PAR-2-mediated signaling in inflammation, pain, and cancer research using in vitro cellular assays.
Product Specifications
CAS Number
313986-65-1
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery, Protein Biochemistry
Smiles
O=C (C1=NN2C (N=C (C=C2C (F) (F) F) C=3C=CC=CC3) =C1) N4CCN (C (=O) C=5C=CC=CC5) CC4
Molecular Formula
C25H20F3N5O2
Molecular Weight
479.454
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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