Tubulin polymerization-IN-72
Tubulin polymerization-IN-72 (Compound 4a4) is a potent colchicine-site microtubule inhibitor with sub-nanomolar IC50 values (0.4-2.7 nM) . It blocks tubulin assembly, causing G2/M phase arrest and apoptosis in cancer cells, supporting its investigation in anticancer research both in vitro and in vivo.
Product Specifications
Field of Research
Cell Biology, Signal Transduction
Smiles
CNC1=NC2=C (C=C (C=C2) F) C (=N1) N3CCCC4=C3C=CC (=C4) OC
Molecular Formula
C19H19FN4O
Molecular Weight
338.379
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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