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Tubulin polymerization-IN-72

Tubulin polymerization-IN-72 (Compound 4a4) is a potent colchicine-site microtubule inhibitor with sub-nanomolar IC50 values (0.4-2.7 nM) . It blocks tubulin assembly, causing G2/M phase arrest and apoptosis in cancer cells, supporting its investigation in anticancer research both in vitro and in vivo.

Product Specifications

Field of Research

Cell Biology, Signal Transduction

Smiles

CNC1=NC2=C (C=C (C=C2) F) C (=N1) N3CCCC4=C3C=CC (=C4) OC

Molecular Formula

C19H19FN4O

Molecular Weight

338.379

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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