TRK-IN-30
TRK-IN-30 (Compound C11) is a potent pan-TRK inhibitor effective against TRKA, TRKB, TRKC, and the TRKAG595R mutant. It blocks downstream PI3K/AKT and MEK/ERK signaling, leading to suppressed proliferation, cell cycle arrest, and apoptosis in cancer cells like Km-12, making it a valuable tool for oncology research in vitro.
Product Specifications
Field of Research
Cell Biology, Signal Transduction
Smiles
COC1=C (C=C (C=C1) NC (=O) C2=C (C (=CC=C2) NC3=CC4=C (C=C3) C (=CN4) C#N) N) OC
Molecular Formula
C24H21N5O3
Molecular Weight
427.455
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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