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TRK-IN-30

TRK-IN-30 (Compound C11) is a potent pan-TRK inhibitor effective against TRKA, TRKB, TRKC, and the TRKAG595R mutant. It blocks downstream PI3K/AKT and MEK/ERK signaling, leading to suppressed proliferation, cell cycle arrest, and apoptosis in cancer cells like Km-12, making it a valuable tool for oncology research in vitro.

Product Specifications

Field of Research

Cell Biology, Signal Transduction

Smiles

COC1=C (C=C (C=C1) NC (=O) C2=C (C (=CC=C2) NC3=CC4=C (C=C3) C (=CN4) C#N) N) OC

Molecular Formula

C24H21N5O3

Molecular Weight

427.455

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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