BCR-ABL-IN-11
BCR-ABL-IN-11 (Compound 2) is a small molecule BCR-ABL inhibitor with demonstrated in vitro anticancer activity against chronic myelogenous leukemia (CML), showing an IC50 of 129.61 μM in K562 cells. It serves as a research tool for studying BCR-ABL-driven oncogenesis and screening for potential CML therapeutics.
Product Specifications
CAS Number
2362-25-6
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
O=C (NC1=CC=CC (=C1) NC (=O) C2=CC=C (N) C=C2) C3=CC=C (N) C=C3
Molecular Formula
C20H18N4O2
Molecular Weight
346.383
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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