PDE5-IN-13
PDE5-IN-13 (Compound 14b) is a potent and selective PDE5A inhibitor (IC50 = 3 nM) with oral bioavailability. It is a valuable research tool for investigating pulmonary arterial hypertension, suitable for both in vitro enzymatic assays and in vivo pharmacokinetic and efficacy studies.
Product Specifications
Field of Research
Metabolism Research, Signal Transduction
Smiles
C[C@H] (C1=CC=CC=N1) NC2=CC=CC3=C2N (C (=O) C (=C3C4=CC=C (C=C4) OC) C#N) CC5=CC=CC=C5
Molecular Formula
C31H26N4O2
Molecular Weight
486.564
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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