SPA0355
SPA0355 is a thiourea-based small molecule that inhibits osteoclast formation and promotes osteoblast differentiation. It suppresses RANKL-induced MAPK, Akt, and NF-κB pathways in vitro and protects against bone loss in ovariectomized mouse models, making it a valuable research tool for studying bone metabolism and osteoporosis.
Product Specifications
CAS Number
1251839-15-2
Field of Research
Signal Transduction
Smiles
S=C (NC1=CC=C (OCCN2C=3C=CC=CC3OC=4C=CC=CC42) C=C1) NC
Molecular Formula
C22H21N3O2S
Molecular Weight
391.486
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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