FLT3-IN-28
FLT3-IN-28 is an orally bioavailable FLT3 inhibitor that selectively targets FLT3-ITD mutations, demonstrating potent activity in AML cell lines like MV4-11 and MOLM-13 and inducing apoptosis. It shows significant in vivo efficacy, extending survival in MOLM-13 xenograft models, making it a valuable tool for FLT3-ITD+ cancer research.
Product Specifications
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction, Stem Cell & Developmental Biology
Smiles
C1C (CN1C (=O) NC2=NC=CC (=C2) OC3=C (C=C (C=C3) NC (=O) C4=CN (N=N4) C5=CN=CC=C5) F) O
Molecular Formula
C23H19FN8O4
Molecular Weight
490.447
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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