NVP-QAV-572

NVP-QAV-572 is a PI3K inhibitor extracted from patent US7998990B2, Compound Example 8, has an IC50 of 10 nM.

Product Specifications

CAS Number

[957209-68-6]

UNSPSC

12352005

Target

PI3K

Type

Reference compound

Related Pathways

PI3K/Akt/mTOR

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/nvp-qav-572.html

Purity

98.53

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(NC1=NC(C)=C(C2=CC=C(S(=O)(C)=O)C(F)=C2)S1)NCCC3=NN(CCF)N=N3

Molecular Formula

C17H19F2N7O3S2

Molecular Weight

471.50

References & Citations

[1]Emma Budd, et al. 5-phenyl-thiazol-2-yl-urea derivatives and use as PI3 kinase inhibitors. US 7998990 B2.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PI3K

Available Sizes

Curated Selection

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