HPK1-IN-56
HPK1-IN-56 (Compound A29) is a potent HPK1 inhibitor with single-digit nM IC50 values in biochemical and cellular assays. It promotes IL-2 production in human PBMCs and enhances T-cell function, supporting research into its potential to improve anticancer immunotherapies, such as in combination with anti-PD-1 antibodies.
Product Specifications
CAS Number
2901054-39-3
Field of Research
Immunology & Inflammation, Signal Transduction
Smiles
N1=NC=2C (N=C1NC=3C=C4C (=CC3OC) CCN (C) C4) =CC (=CC2N) C=5C=NC=C (N) C5C
Molecular Formula
C24H26N8O
Molecular Weight
442.516
Storage Conditions
-20°C
Notes
For research use only.
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