EGFR-IN-136
EGFR-IN-136 (compound 21v) is a potent EGFR inhibitor with IC50 values ranging from 1.2 to 20.2 nM against various EGFR mutants, including those relevant to NSCLC. It demonstrates antiproliferative activity in vitro and antitumor efficacy in vivo, making it a valuable tool for oncology research, particularly in studying resistance mechanisms and targeted therapies for non-small cell lung cancer.
Product Specifications
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
CC1=CN=C2NC3=C (C=C (C (=C3) C4=CN (CCCOC5=CC (=C (C=C5) NC1=N2) P (=O) (C) C) N=C4) N6CCOCC6) OC
Molecular Formula
C30H36N7O4P
Molecular Weight
589.625
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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