ER degrader 10
ER degrader 10 (Compound 51) is a potent, orally bioavailable, and brain-penetrant selective estrogen receptor degrader (SERD) and antagonist. It demonstrates potent anti-proliferative activity in ER+ breast cancer cell lines and shows in vivo antitumor efficacy in mouse models, supporting its use in oncology research.
Product Specifications
CAS Number
3035311-43-1
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Smiles
O (C) C1=C ([C@@H]2[C@@H] (C=3C (SC2) =CC (O) =CC3) C4=CC=C (OCCN5CC (CF) C5) C=C4) C=CC (F) =C1
Molecular Formula
C28H29F2NO3S
Molecular Weight
497.597
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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