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YAP/TEAD-IN-1

YAP/TEAD-IN-1 (compound 4) is a potent and selective small molecule inhibitor of the YAP-TEAD protein-protein interaction, a key oncogenic driver in the Hippo signaling pathway. It exhibits antiproliferative activity against various cancer cell lines in vitro and has shown antioxidant properties with minimal cytotoxicity to normal human cells, making it a valuable research tool for studying Hippo pathway biology and cancer.

Product Specifications

Field of Research

Cancer Biology, Stem Cell & Developmental Biology

Smiles

CN (C) C1=CC=C (C=C1) C2CC (=NN2C3=CC=CC=C3) C4=CC=C (C=C4) N=NC5C (=NN (C5=O) C6=CC=CC=C6) N

Molecular Formula

C32H30N8O

Molecular Weight

542.634

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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