L-657926
L-657926 is a stereoselective thromboxane A2 (TxA2) receptor antagonist, where the (-) -enantiomer exhibits high potency (IC50 = 0.27 nM) compared to the (+) -enantiomer (IC50 = 124 nM) . This compound is a valuable research tool for investigating TxA2-mediated pathways in cardiovascular and thrombotic diseases, applicable in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
113243-00-8
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery
Smiles
C (N1C2=C (C=3C1=CC=C (F) C3) CCC[C@H]2CC (O) =O) C4=CC=C (Cl) C=C4
Molecular Formula
C21H19ClFNO2
Molecular Weight
371.832
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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