BRD4 Inhibitor-38
BRD4 Inhibitor-38 (Compound 25) is an orally bioavailable small molecule with selectivity for the BD2 domain of BRD4 (IC50s: 3.64 μM BD1, 0.12 μM BD2) . It exhibits anti-inflammatory activity by inhibiting nitric oxide production (IC50 = 1.98 μM) and is a useful chemical probe for studying BRD4 function in oncology and inflammation research, both in vitro and in vivo.
Product Specifications
Field of Research
Cell Biology, Epigenetics & Chromatin, Epigenetics & Chromatin; Pharmacology & Drug Discovery, Immunology & Inflammation
Smiles
COC1=CC=C (C=C1) /C=C/C2=NC3=C (C (=CC (=C3) OC) OC) C (=O) N2
Molecular Formula
C19H18N2O4
Molecular Weight
338.357
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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