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CSRC/BCR-ABL-IN-1

CSRC/BCR-ABL-IN-1 (compound 21b) is a dual inhibitor of Bcr-Abl and c-Src kinases, demonstrating potent activity with IC50 values of 56.2 nM and 101 nM, respectively. This cytotoxic compound is a valuable chemical tool for investigating kinase signaling in cancer research, applicable in both cellular and biochemical assays.

Product Specifications

Field of Research

Cardiovascular Research, Cell Biology, Signal Transduction

Smiles

CN1CCN (CC1) CCCOC2=C (C=C3C (=C2) N=CC (=C3N (C4=CC (=C (C=C4Cl) Cl) OC) C (=O) C=C) C#N) OC

Molecular Formula

C29H31Cl2N5O4

Molecular Weight

584.494

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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