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PROTAC HDAC6 degrader 2

Compound 1 (PROTAC HDAC6 degrader 2) is a potent degrader of HDAC6 with an IC50 of 0.643 μM, inducing its ubiquitination and proteasomal degradation. This tool compound is utilized in cancer research, supporting in vitro and in vivo studies for both hematological malignancies and solid tumors.

Product Specifications

Field of Research

Epigenetics & Chromatin, Molecular Biology, Pharmacology & Drug Discovery

Smiles

C1CC (=O) NC (=O) C1N2C (=O) C3=C (C2=O) C (=CC=C3) NCCOCCOCC (=O) NCC4=CC=CC (=C4) CNC5=NC=C (C=N5) C6=NN=C (O6) C (F) F

Molecular Formula

C34H33F2N9O8

Molecular Weight

733.678

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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