PROTAC HDAC6 degrader 2
Compound 1 (PROTAC HDAC6 degrader 2) is a potent degrader of HDAC6 with an IC50 of 0.643 μM, inducing its ubiquitination and proteasomal degradation. This tool compound is utilized in cancer research, supporting in vitro and in vivo studies for both hematological malignancies and solid tumors.
Product Specifications
Field of Research
Epigenetics & Chromatin, Molecular Biology, Pharmacology & Drug Discovery
Smiles
C1CC (=O) NC (=O) C1N2C (=O) C3=C (C2=O) C (=CC=C3) NCCOCCOCC (=O) NCC4=CC=CC (=C4) CNC5=NC=C (C=N5) C6=NN=C (O6) C (F) F
Molecular Formula
C34H33F2N9O8
Molecular Weight
733.678
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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