EGFR T790M/L858R-IN-9
EGFRT790M/L858R-IN-9 (Compound 8) is a potent and selective inhibitor of the EGFR-L858R/T790M mutant kinase, with an IC50 of 6.4 nM. It effectively blocks mutant EGFR phosphorylation and suppresses the proliferation of NSCLC cells in vitro, serving as a valuable tool for targeted cancer therapy research.
Product Specifications
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
CCC (=O) N1CCN (CC1) C2=CC (=CC=C2) OC3=NC=CC (=N3) NC4=NN=C (S4) C5=CC=C (C=C5) OC
Molecular Formula
C26H27N7O3S
Molecular Weight
517.603
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC740525-100 1x 100 µL
CD63 (MX-49.129.5), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC040181-500 1x 500 µL
CD59 (heavy chain of Protectin) (BRA-10G), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC941037-500 1x 500 µL
CD44 Standard (DF1485), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC040965-100 1x 100 µL
MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (VU-11D1), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC470270-100 1x 100 µL
Fibronectin (HFN7.1), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC041947-100 1x 100 µL
Cytokeratin 10 (Suprabasal Epithelial Marker) (rKRT10/1275), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details