PKZ18
PKZ18 is a research antibiotic active against Gram-positive bacteria (MIC 32-64 μg/mL) . It functions by targeting the T-box riboswitch, specifically stem I specifier loops, to inhibit transcription readthrough and disrupt glycyl-tRNA synthetase expression, offering a mechanism with a low propensity for resistance development.
Product Specifications
CAS Number
849658-87-3
Field of Research
Infectious Disease & Virology
Purity
98.08% (May vary between batches)
Smiles
C (NC1=NC (=C (C) S1) C2=CC=C (C (C) C) C=C2) (=O) [C@@H]3[C@H] (C (O) =O) [C@@]4 (C[C@]3 (CC4) [H]) [H]
Molecular Formula
C22H26N2O3S
Molecular Weight
398.52
Storage Conditions
-20°C
Notes
For research use only.
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