Avitinib maleate dihydrate
Avitinib maleate dihydrate is an irreversible, orally active EGFR inhibitor with high selectivity for mutant forms (L858R/T790M) over wild-type. It also acts as a BTK inhibitor, showing anticancer activity in vitro by inducing apoptosis and inhibiting BTK phosphorylation in lymphoma cell models.
Product Specifications
CAS Number
1822357-78-7
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
OC (/C=C\C (O) =O) =O.FC1=C (N2CCN (CC2) C) C=CC (NC3=NC (OC4=CC (NC (C=C) =O) =CC=C4) =C5C (NC=C5) =N3) =C1.O.O
Molecular Formula
C30H34FN7O8
Molecular Weight
639.631
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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