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Avitinib maleate dihydrate

Avitinib maleate dihydrate is an irreversible, orally active EGFR inhibitor with high selectivity for mutant forms (L858R/T790M) over wild-type. It also acts as a BTK inhibitor, showing anticancer activity in vitro by inducing apoptosis and inhibiting BTK phosphorylation in lymphoma cell models.

Product Specifications

CAS Number

1822357-78-7

Field of Research

Cardiovascular Research, Cell Biology, Signal Transduction

Smiles

OC (/C=C\C (O) =O) =O.FC1=C (N2CCN (CC2) C) C=CC (NC3=NC (OC4=CC (NC (C=C) =O) =CC=C4) =C5C (NC=C5) =N3) =C1.O.O

Molecular Formula

C30H34FN7O8

Molecular Weight

639.631

Storage Conditions

-20°C

Notes

For research use only.

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